Studies of interactions of STIM1 and GPCRs with their binding partners

• Main Author: How, Jonathan Guan Zhong
• Other Authors: Said Eshaghi
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/65666
• Institution: Nanyang Technological University

Membrane proteins are responsible for cellular functions such as cell signalling and ion transport. Almost half of all modern medicinal drugs have membrane proteins as their targets. In this thesis, focus is on two transmembrane proteins: Adenosine A2A receptor (A2aR) as a model for G-protein couple...