Characterization of progesterone receptor isoform-selective activities of progesterone receptor modulators in breast cancer cells.

This study reveals the effects of progesterone receptor modulators (PRMs) mediated by PR isoforms in PR-transfected MDA-MB-231 cells. Through PR-A and PR-B, PRMs CP8668, AED and Dex-Mes exhibited progesterone agonist effect in which they induced cell spreading, focal adhesion, cell migration and inh...

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Bibliographic Details
Main Author: Leo, Joyce Ching Li.
Other Authors: Lin, Valerie Chun Ling
Format: Theses and Dissertations
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10356/6571
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Institution: Nanyang Technological University