Identification of host factors required for Ty1 transposition in yeast

Tyl is a retrotransposon with a life cycle similar to that of retroviruses. In this project we used the budding yeast Saccharomyces cerevisiae to identifyhost factors necessary for Tyl transposition. The nuclear pore complex (NPC) resides on the membrane of the nuclear envelope (NE) and acts as a ga...

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Main Author: Jin, Shiyi
Other Authors: Thirumaran Thanabalu
Format: Theses and Dissertations
Language:English
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/10356/6581
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-65812019-12-10T14:12:26Z Identification of host factors required for Ty1 transposition in yeast Jin, Shiyi Thirumaran Thanabalu School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology::Virology Tyl is a retrotransposon with a life cycle similar to that of retroviruses. In this project we used the budding yeast Saccharomyces cerevisiae to identifyhost factors necessary for Tyl transposition. The nuclear pore complex (NPC) resides on the membrane of the nuclear envelope (NE) and acts as a gateway for macromolecular transportation between the cytoplasm and the nucleus. A major class of proteins, which is localized to discrete regions of the NPC, is called nucleoporins. In this study 15 mutant yeast strains each with a non-essential nucleoporin deletion were used to carry out the transposition assay. ​Master of Science 2008-09-17T11:42:12Z 2008-09-17T11:42:12Z 2005 2005 Thesis http://hdl.handle.net/10356/6581 en Nanyang Technological University 133 p. application/pdf
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Science::Biological sciences::Microbiology::Virology
spellingShingle DRNTU::Science::Biological sciences::Microbiology::Virology
Jin, Shiyi
Identification of host factors required for Ty1 transposition in yeast
description Tyl is a retrotransposon with a life cycle similar to that of retroviruses. In this project we used the budding yeast Saccharomyces cerevisiae to identifyhost factors necessary for Tyl transposition. The nuclear pore complex (NPC) resides on the membrane of the nuclear envelope (NE) and acts as a gateway for macromolecular transportation between the cytoplasm and the nucleus. A major class of proteins, which is localized to discrete regions of the NPC, is called nucleoporins. In this study 15 mutant yeast strains each with a non-essential nucleoporin deletion were used to carry out the transposition assay.
author2 Thirumaran Thanabalu
author_facet Thirumaran Thanabalu
Jin, Shiyi
format Theses and Dissertations
author Jin, Shiyi
author_sort Jin, Shiyi
title Identification of host factors required for Ty1 transposition in yeast
title_short Identification of host factors required for Ty1 transposition in yeast
title_full Identification of host factors required for Ty1 transposition in yeast
title_fullStr Identification of host factors required for Ty1 transposition in yeast
title_full_unstemmed Identification of host factors required for Ty1 transposition in yeast
title_sort identification of host factors required for ty1 transposition in yeast
publishDate 2008
url http://hdl.handle.net/10356/6581
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