Identification of host factors required for Ty1 transposition in yeast

• Main Author: Jin, Shiyi
• Other Authors: Thirumaran Thanabalu
• Format: Theses and Dissertations
• Language: English
• Published: 2008
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology
• Online Access: http://hdl.handle.net/10356/6581
• Institution: Nanyang Technological University

Tyl is a retrotransposon with a life cycle similar to that of retroviruses. In this project we used the budding yeast Saccharomyces cerevisiae to identifyhost factors necessary for Tyl transposition. The nuclear pore complex (NPC) resides on the membrane of the nuclear envelope (NE) and acts as a ga...