Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications

• Main Author: Zhang, Simin
• Other Authors: Anders Vahlne
• Format: Theses and Dissertations
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Biological sciences::Biochemistry; DRNTU::Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/65839
• Institution: Nanyang Technological University

Class I viral fusion glycoproteins facilitate fusion of the viral envelope with cell membranes and entry of the virus into the cell, through extensive short sequence-specific interactions. Regions mediating these interactions include the N-terminal hydrophobic fusion peptide, a pair of extended 4,3-...