Epigenetic and genetic mechanisms through which Myostatin regulates muscle wasting

Myostatin (Mstn) is a secreted growth factor that negatively regulates proliferation and differentiation of myoblasts. While the downstream signaling pathways and targets genes of Myostatin have been well studied, the involvement of microRNAs (miRNAs) in Myostatin regulation of myogenesis remains to...

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Bibliographic Details
Main Author: Lua, Gavian Bing Jia
Other Authors: Ravi Kambadur
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/65954
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Institution: Nanyang Technological University
Language: English