Microfluidics size fractionation of paclitaxel-loaded microspheres for breast cancer treatment

• Main Author: Tan, Kah Kee
• Other Authors: Loo Say Chye Joachim
• Format: Final Year Project
• Language: English
• Published: 2016
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/66444
• Institution: Nanyang Technological University

Drug-loaded microspheres are widely used in cancer treatment through targeted and sustained drug delivery. In this study, poly(lactic-co-glycolic acid) (PLGA) microspheres loaded with paclitaxel (PTX) are synthesized and size-fractionated using a novel inertial microfluidics strategy (Dean Flow Frac...