2D transport of magnetic microbeads on ferromagnetic network structure

• Main Author: LI, Zhen
• Other Authors: Lew Wen Siang
• Format: Final Year Project
• Language: English
• Published: 2016
• Subjects: DRNTU::Science::Physics::Electricity and magnetism
• Online Access: http://hdl.handle.net/10356/67039
• Institution: Nanyang Technological University

Many scientists and engineers are turning to lab-on-a-chip systems for faster and cheaper analysis of chemical reactions and biomolecular interactions. A common approach that facilitates the handling of reagents and biomolecules in these systems utilizes micro/nano magnetic particles as the carrier. Physical manipulation of biomolecules such as transport, sorting and tweezing can be achieved by fully utilizing the potentials of these magnetic particles. Past work demonstrated manipulation of micro- and nano-magnetic particles either with nanoscale accuracy over a limited spatial area or loss of spatial accuracy. Limitations in the precise control of magnetic particles. Remote manipulation of fluid-borne magnetic particles is required to meet the demand for high throughput and location-specific analysis. Techniques develop to encompass capture, translocation along multiple trajectories and release of magnetic particles have yet to be achieved. In this work, we introduce method that employs arrays of discrete patterned magnetic thin films micro-structures to form transport lines that enable the motion of magnetic particles when subjected to an external magnetic field by Three Axis Magnetic Coil Setup (TMCS). Patterned magnetic thin films were fabricated using Electron Beam Lithography (EBL) and Magnetron Sputtering techniques. We also demonstrates the trapping and precise controlled motion of 1um magnetic particles via strong localized fields and gradients found at domain walls in patterned magnetic thin films. The Propagation of magnetic domain walls in patterned magnetic thin films can magnetostatically couple to magnetic particles. In combination with manipulation of magnetostatic potential energy of domain walls, a new possibility which encompass capture; translocation along multiple trajectories; transportation over large distances, and release of magnetic particles are established. The proposed technology is simple and easy to produce and can be used to enhance applications in biology, chemistry and medicine. However, this type of manipulation has limited number of patterned magnetic thin films.