Chromatin changes induced by nuclear lamina in embryonic stem cell

The Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder caused by a mutation in the LMNA gene, which leads to the premature ageing of affected children. This mutation triggers the production of progerin, a truncated form of the lamin A protein. Progerin has recently been shown to...

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Bibliographic Details
Main Author: Siah, Chia Keng
Other Authors: Colin Stewart
Format: Final Year Project
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/67170
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Institution: Nanyang Technological University
Language: English