Investigating the effect of betamethasone loaded lipid-polymer hybrid nanoparticles for autoimmune diseases

• Main Author: Su, Isabella Jing Tian
• Other Authors: Chan Shuping Juliana Maria
• Format: Final Year Project
• Language: English
• Published: 2016
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/68405
• Institution: Nanyang Technological University

Presently, the use of nanoparticles (NP) to encapsulate and deliver drugs for treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis focus on targeting macrophages to reduce inflammatory response. Tumor necrosis factor alpha (TNF-α) is expressed by macrophages during inflammatio...