Effect of stress on Parkinsonian Phenotypes in Leucine-rich Repeat Kinase 2 LRRK2 (R1441G) mice mutants

Effect of stress on Parkinsonian Phenotypes in Leucine-rich Repeat Kinase 2 LRRK2 (R1441G) mice mutants

Parkinson’s disease (PD) is a progressive age related neurodegenerative disorder that affects 13% of the general population above the age of 65. The etiology of Parkinson's is multifactorial and can often involve a variety of factors such as i) genetic mutations and ii) environmental stresso...

Saved in:

書目詳細資料
主要作者:	Rahavan, R.
其他作者:	Zoe Bichler
格式:	Final Year Project
語言:	English
出版:	2016
主題:	DRNTU::Science
在線閱讀:	http://hdl.handle.net/10356/68617
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

相似書籍

Targeting leucine-rich repeat kinase 2 in Parkinson's disease
由: Chan S.L., et al.
出版: (2018)

Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease
由: Haugarvoll K., et al.
出版: (2018)

Identification of protein phosphatase 2A as an interacting protein of leucine-rich repeat kinase 2
由: Athanasopoulos P.S., et al.
出版: (2018)

Case-control analysis of leucine-rich repeat kinase 2 protective variants in Alzheimer's disease
由: Ng A.S.L., et al.
出版: (2018)

Effect of stress on neuroinflammation in the substantia nigra and striatum of LRRK2 (R1441G) mouse model for Parkinson’s disease
由: Chen, Jiayi
出版: (2015)

Investigations on the tissue distribution, localization and functions of brain-enriched leucine-rich repeats (LRR) containing proteins AMIGO AND NgR2
由: CHEN YANAN
出版: (2011)

Dysregulated dopamine metabolism in LRRK2 mutants
由: Chia, Xin Tian
出版: (2015)

MINISEED3 (MINI3), a WRKY family gene, and HAIKU2 (IKU2), a leucine-rich repeat (LRR) KINASE gene, are regulators of seed size in Arabidopsis
由: Luo, M., et al.
出版: (2016)

Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis
由: Sulochana, K.N., et al.
出版: (2014)

Identification of targets from lrrk2 rescue phenotypes
由: Toh, Joanne, et al.
出版: (2022)

MAP1B rescues LRRK2 mutant-mediated cytotoxicity
由: Chan S.L., et al.
出版: (2018)

Leptospira borgpetersenii hybrid leucine-rich repeat protein: Cloning and expression, immunogenic identification and molecular docking evaluation
由: Tepyuda Sritrakul, et al.
出版: (2018)

Non-Motor and Motor Features in LRRK2 Transgenic Mice
由: Bichler, Z., et al.
出版: (2014)

Phenotype detection in morphological mutant mice using deformation features.
由: Roy, S., et al.
出版: (2014)

Phenotype detection in morphological mutant mice using deformation features
由: Roy, S., et al.
出版: (2014)

Roles of leucine-rich alpha-2-glycoprotein 1 in normal and diabetic wound healing
由: Liu, Chenghao
出版: (2019)

High expression of a novel leucine-rich repeat protein in hemocytes and the lymphoid organ of the black tiger shrimp Penaeus monodon
由: Thanawat Sriphaijit, et al.
出版: (2018)

Thiol peroxidases ameliorateLRRK2mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila
由: Angeles, D.C., et al.
出版: (2016)

Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila
由: Ng, C.-H., et al.
出版: (2014)

The role of leucine-rich alpha-2-glycoprotein 1 (LRG1) in colorectal cancer cells
由: Chew, Clement Kai Hong
出版: (2016)

Lrrk2 R1628P in non-Chinese Asian races
由: Tan, E.-K., et al.
出版: (2014)

Essential tremor and the common LRRK2 G2385R variant
由: Tan E.-K., et al.
出版: (2018)

Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease
由: Chen Z.-C., et al.
出版: (2018)

Parkinsonian syndromes: A review
由: Prachaya Srivanitchapoom, et al.
出版: (2019)

Exploring the role of leucine-rich alpha-2-glycoprotein 1 (LRG1) in the pathophysiology of pancreatic diseases
由: Lim, Seok Ting
出版: (2021)

The role of leucine-rich alpha-2 glycoprotein 1 (LRG1) in diabetes-related ischaemic heart diseases
由: Chia, Rui Ning
出版: (2019)

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease
由: Ross, O.A., et al.
出版: (2014)

Lrrk2 R1628P variant is a risk factor for essential tremor
由: Chao Y.X., et al.
出版: (2018)

LRRK2 R1628P increases risk of Parkinson's disease: Replication evidence
由: Tan, E.K., et al.
出版: (2014)

The role of Leucine Repeat Adaptor Protein 25(LRAP25), a novel interactor of Myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) in mediating lamellipodial F-actin dynamics
由: LEE CHENG JIE, IRENE
出版: (2011)

Leucine Rich Alpha-2-Glycoprotein 1 Is A Novel Predictor Of Diastolic Dysfunction: A Cross-Sectional Study
由: Loch, Alexander, et al.
出版: (2021)

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
由: West A.B., et al.
出版: (2018)

AMIGO and friends: An emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs
由: Chen, Y., et al.
出版: (2011)

To analyze the effects of leucine-rich alpha-2 glycoprotein-1 (LRG1) on angiogenesis in diabetes associated ischemic heart disease
由: Lee, Charmaine Zhi Ning
出版: (2017)

Leucine-Rich ?-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-? Receptor
由: Pang, Kuin Tian, et al.
出版: (2022)

LRRK2 G2385R and R1628P Mutations Are Associated with an Increased Risk of Parkinson's Disease in the Malaysian Population
由: Gopalai A.A., et al.
出版: (2018)

Frequencies of LRRK2 variants in Thai patients with Parkinson's disease: Evidence for an R1628P founder
由: Teeratorn Pulkes, et al.
出版: (2018)

Iron and cell death in Parkinson's disease: A nuclear microscopic study into iron-rich granules in the parkinsonian substantia nigra of primate models
由: Thong, P.S.P., et al.
出版: (2012)

Modulation of parvalbumin expression in the motor cortex of parkinsonian rats
由: Capper-Loup, C., et al.
出版: (2014)

LRRK2 variant associated with Alzheimer's disease
由: Zhao, Y., et al.
出版: (2014)