Production of Nipah Virus VLPs
The Nipah Virus (NiV) is an emerging infectious virus that has caused outbreaks since 1998. It is a dangerous zoonotic virus with a 40-75% case fatality rate and the route of transmission is skewed towards human-to-human transmission in recent year. With no treatment available and only one vaccine t...
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2016
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sg-ntu-dr.10356-688132023-02-28T18:07:27Z Production of Nipah Virus VLPs Ng, Say Yong Richard J Sugrue School of Biological Sciences DRNTU::Science::Biological sciences::Microbiology::Virology The Nipah Virus (NiV) is an emerging infectious virus that has caused outbreaks since 1998. It is a dangerous zoonotic virus with a 40-75% case fatality rate and the route of transmission is skewed towards human-to-human transmission in recent year. With no treatment available and only one vaccine that is licensed for horses, this necessitates the new treatments and vaccine urgently. Classified as a BSL4 virus, the research that can be done on it will hampers the development of new therapeutics. In this study we managed to culture and isolation Nipah virus-like particles in a BSL2 laboratory. This Nipah VLPs has the viral glycoproteins as an authentic virus but without any genetic material and is a potential vaccine. Bachelor of Science in Biological Sciences 2016-06-03T04:11:17Z 2016-06-03T04:11:17Z 2016 Final Year Project (FYP) http://hdl.handle.net/10356/68813 en Nanyang Technological University 33 p. application/pdf |
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DRNTU::Science::Biological sciences::Microbiology::Virology Ng, Say Yong Production of Nipah Virus VLPs |
| description |
The Nipah Virus (NiV) is an emerging infectious virus that has caused outbreaks since 1998. It is a dangerous zoonotic virus with a 40-75% case fatality rate and the route of transmission is skewed towards human-to-human transmission in recent year. With no treatment available and only one vaccine that is licensed for horses, this necessitates the new treatments and vaccine urgently. Classified as a BSL4 virus, the research that can be done on it will hampers the development of new therapeutics. In this study we managed to culture and isolation Nipah virus-like particles in a BSL2 laboratory. This Nipah VLPs has the viral glycoproteins as an authentic virus but without any genetic material and is a potential vaccine. |
| author2 |
Richard J Sugrue |
| author_facet |
Richard J Sugrue Ng, Say Yong |
| format |
Final Year Project |
| author |
Ng, Say Yong |
| author_sort |
Ng, Say Yong |
| title |
Production of Nipah Virus VLPs |
| title_short |
Production of Nipah Virus VLPs |
| title_full |
Production of Nipah Virus VLPs |
| title_fullStr |
Production of Nipah Virus VLPs |
| title_full_unstemmed |
Production of Nipah Virus VLPs |
| title_sort |
production of nipah virus vlps |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10356/68813 |
| _version_ |
1759853319912685568 |