Evaluation of paper spray mass spectrometry for direct analysis of small molecule drugs and hemoglobin constant spring peptide markers

• Main Author: Takyi-Williams, John
• Other Authors: Tang Kai
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Science::Chemistry::Analytical chemistry::Qualitative analysis; DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology; DRNTU::Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/68927
• Institution: Nanyang Technological University

A significant limitation in performing preclinical studies using small animals is the need for macrovolume blood sampling, a similar situation encountered with newborn or neonates screening. Dried blood spot (DBS) method which requires small sample volume has overcome this limitation. However, the r...