Identification of potential common cyclic-di-GMP regulated biomarkers among three gram negative bacteria via transcriptomic and metabolomic profiling

• Main Author: Cai, Zhao
• Other Authors: Staffan Kjelleberg
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/69468
• Institution: Nanyang Technological University

Bacterial cells can switch between two life styles, namely planktonic and biofilm, depending on different environmental cues. Biofilms are involved in almost 80% of microbial infections. Biofilm infections can evade host immune attack and develop into chronic conditions, which cannot be efficiently...