Solution X-ray scattering studies on the dengue virus non-structural protein 5 and -3 as well as the capsid protein

• Main Author: Saw, Wuan Geok
• Other Authors: Gerhard Gruber
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Virology; DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/69574
• Institution: Nanyang Technological University

Dengue virus (DENV), which is the causative agent of dengue, is a single positive-stranded RNA virus. The structural information of two DENV non-structural proteins, NS5 and NS3, which play a central role in the genome replication, were gathered using small-angle X-ray scattering (SAXS). SAXS reveal...