Photochrome aptamer switch assay (PHASA) for small molecule detection and quantification

• Main Author: Wu, Yuanyuan
• Other Authors: Terry W. J. Steele
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Engineering::Materials
• Online Access: http://hdl.handle.net/10356/69575
• Institution: Nanyang Technological University

In order to detect small analytes with high specificity and efficiency that cannot otherwise be achieved by antibody–based immunoassays, the development of a new Photochrome Aptamer Switch Assay (PHASA) was explored. In this assay, aptamer which can be synthesized chemically and can bind small molec...