Development of in vitro and in vivo models to characterize biofilm formation by a necrotizing strain of Group A Streptococcus

• Main Author: Anuradha Vajjala
• Other Authors: Emanuel Hanski
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/70164
• Institution: Nanyang Technological University

Group A Streptococcus (GAS) causes a wide variety of human diseases, ranging from mild, self-limiting infections to highly invasive life-threatening diseases such as necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS). In accordance, GAS is the fourth most common bacterial cause...