The effect of the amyloid-beta peptide on the fluidity of cell membranes : a study by fluorescence correlation spectroscopy

• Main Author: Ng, Justin Wei Qing
• Other Authors: Roger D. Kamm
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences::Biochemistry; DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/70210
• Institution: Nanyang Technological University

Alzheimer’s disease (AD) is an age-related neurodegenerative disease which affects up to 80% of patients presenting dementia. One of the key factors thought lead to AD is the aggregation of the amyloid-beta (Aβ) in susceptible brain regions, namely the cerebral cortex and hippocampus. Aβ is thought...