Biology of murine CD84 in the context of autoimmunity
Systemic lupus erythematosus (SLE) is characterized by the production of autoantibodies (ANAs), these form self-reactive immune complexes with self-antigens which results in tissue inflammation. The SLAM family (SLAMF) receptors are regulators of the innate and adaptive immune response. In mice,...
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sg-ntu-dr.10356-711722023-02-28T18:44:42Z Biology of murine CD84 in the context of autoimmunity Olga Zharkova Anna-Marie Fairhurst School of Biological Sciences DRNTU::Science Systemic lupus erythematosus (SLE) is characterized by the production of autoantibodies (ANAs), these form self-reactive immune complexes with self-antigens which results in tissue inflammation. The SLAM family (SLAMF) receptors are regulators of the innate and adaptive immune response. In mice, SLAMF are located within the sle1 lupussusceptibility locus. When present on a B6 background, sle1 drives B and T cell hyperreactivity and ANAs production. Doctor of Philosophy (SBS) 2017-05-15T06:39:30Z 2017-05-15T06:39:30Z 2017 Thesis http://hdl.handle.net/10356/71172 10.32657/10356/71172 en Nanyang Technological University 200 p. application/pdf |
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DRNTU::Science Olga Zharkova Biology of murine CD84 in the context of autoimmunity |
| description |
Systemic lupus erythematosus (SLE) is characterized by the production of
autoantibodies (ANAs), these form self-reactive immune complexes with self-antigens which
results in tissue inflammation. The SLAM family (SLAMF) receptors are regulators of the
innate and adaptive immune response. In mice, SLAMF are located within the sle1 lupussusceptibility
locus. When present on a B6 background, sle1 drives B and T cell hyperreactivity
and ANAs production. |
| author2 |
Anna-Marie Fairhurst |
| author_facet |
Anna-Marie Fairhurst Olga Zharkova |
| format |
Theses and Dissertations |
| author |
Olga Zharkova |
| author_sort |
Olga Zharkova |
| title |
Biology of murine CD84 in the context of autoimmunity |
| title_short |
Biology of murine CD84 in the context of autoimmunity |
| title_full |
Biology of murine CD84 in the context of autoimmunity |
| title_fullStr |
Biology of murine CD84 in the context of autoimmunity |
| title_full_unstemmed |
Biology of murine CD84 in the context of autoimmunity |
| title_sort |
biology of murine cd84 in the context of autoimmunity |
| publishDate |
2017 |
| url |
http://hdl.handle.net/10356/71172 |
| _version_ |
1759856553919250432 |