Nanoparticle incorporated polymer brush films for sensing interfaces
The use of polymer brushes has been attracting attention in recent years due to its ability to reduce non-specific adsorption of proteins on a surface. At the same time, noble metal nanoparticles has been widely exploited for chemical and biomolecular sensing applications, particularly...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2017
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/72401 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | The use of polymer brushes has been attracting attention in recent years due to its
ability to reduce non-specific adsorption of proteins on a surface. At the same time,
noble metal nanoparticles has been widely exploited for chemical and biomolecular
sensing applications, particularly via localized surface plasmon resonance and surface
enhanced raman spectroscopy. While many conventional plasmonic, nanoparticle
solution-based detection methods offer direct observation with high sensitivity and
selectivity, they have several limitations. For example, it is difficult to discern color
hue or intensity changes in colored samples or complex mixtures such as blood and
serum. Nanoparticle in solution are also prone to aggregation over time, reducing shelf
life. |
|---|