Development of phosphapalladacycles as potential catalysts for asymmetric synthesis

• Main Author: Chiew, Jun Xuan
• Other Authors: Leung Pak Hing
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds; DRNTU::Science::Chemistry::Inorganic chemistry::Metals
• Online Access: http://hdl.handle.net/10356/72660
• Institution: Nanyang Technological University

A series of chiral tertiary phosphine ligands have been prepared via two synthetic approaches, namely through the optical resolution of racemic phosphines, and the asymmetric hydrophosphination reaction of enones with secondary phosphines promoted by chiral palladacycles. The ortho-palladation of th...