Structural and mechanistic insights into Mycothiol disulfide reductase, Mycoredoxin-1 and peroxiredoxin alkyl hydroperoxidase subunit E of Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) has the ability to persist within the human host for a long time in a dormant stage and re-emerges when the immune system is compromised. During infection, Mtb is exposed to a number of redox stresses inside macrophages, such as reactive oxygen species and reactive n...

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Bibliographic Details
Main Author: Kumar, Arvind
Other Authors: Gerhard Gruber
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72805
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Institution: Nanyang Technological University
Language: English