A study of the long non-coding RNA Xist using live-cell imaging

• المؤلف الرئيسي: Ong, Norbert Ha How
• مؤلفون آخرون: Zhang Li-Feng
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences::Genetics
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/73196
• المؤسسة: Nanyang Technological University

A prototype long non-coding RNA (lncRNA) is the Xist RNA (X-inactive specific transcript) in X chromosome inactivation (XCI), a mammalian form of dosage compensation, in which one of the two Xs in each female cell is inactivated to balance the X-linked gene dosage between males and females. The Xist...