Establishing a genetically engineered mouse ES cell line expressing an inducible Xist transgene along chromosome 19
Xist (X-inactive specific transcript) RNA plays an important role in X chromosome inactivation (XCI), a dosage compensation mechanism mammalian females have evolved to transcriptionally silence one of two copies of X chromosomes they carry. Xist RNA remains in the nucleus, and during XCI onset, it i...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2018
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/89676 http://hdl.handle.net/10220/46341 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |