Development of novel gene delivery system for cancer therapy
In this thesis, novel biodegradable charged polyester-based vectors (BCPVs) were designed and synthesized as siRNA carrier for cancer treatment. Under optimized conditions, the BCPV can effectively protect siRNA from degradation by RNase in the serum, and would subsequently promote intracellular siR...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2018
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Online Access: | http://hdl.handle.net/10356/73477 |
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Institution: | Nanyang Technological University |
Language: | English |