Development of novel gene delivery system for cancer therapy

In this thesis, novel biodegradable charged polyester-based vectors (BCPVs) were designed and synthesized as siRNA carrier for cancer treatment. Under optimized conditions, the BCPV can effectively protect siRNA from degradation by RNase in the serum, and would subsequently promote intracellular siR...

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Bibliographic Details
Main Author: Yang, Chengbin
Other Authors: Yong Ken Tye
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73477
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Institution: Nanyang Technological University
Language: English
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