Nucleic acid structures containing g-quadruplex and duplex motifs : a structural study and potential targeting approach
Guanine-rich nucleic acid sequences have the propensity to assume four-stranded structures known as G-quadruplex. G-quadruplex-forming sequences were identified at important regulatory regions in the human genome such as the telomere, gene promoter, and 5’-untranslated region of mRNA. Important biol...
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Format: | Theses and Dissertations |
Language: | English |
Published: |
2018
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Online Access: | http://hdl.handle.net/10356/73601 |
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Institution: | Nanyang Technological University |
Language: | English |