Nucleic acid structures containing g-quadruplex and duplex motifs : a structural study and potential targeting approach

Guanine-rich nucleic acid sequences have the propensity to assume four-stranded structures known as G-quadruplex. G-quadruplex-forming sequences were identified at important regulatory regions in the human genome such as the telomere, gene promoter, and 5’-untranslated region of mRNA. Important biol...

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Bibliographic Details
Main Author: Nguyen, Thi Quynh Ngoc
Other Authors: Phan Anh Tuan
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73601
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Institution: Nanyang Technological University
Language: English