The role of sequence elements and protein interactions in focal subcellular localization of Sortase A in Enterococcus faecalis

• المؤلف الرئيسي: Mitra, Sumitra Debina
• مؤلفون آخرون: Kimberly Kline
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/73628

Sortase A (SrtA) is a transmembrane protein responsible for covalently anchoring several virulence factors and adhesins to the cell wall of Gram-positive organisms, including Enterococci. In E. faecalis, SrtA localizes to single foci at the septum during early division phases and reorients to multip...