In vitro and In vivo characterization of anti-biofilm activity of LpxC inhibitor alone, and in combination with different classes of antimicrobials

Biofilms are multicellular bacterial communities that are formed on a surface and encased in extracellular polymeric substance (EPS) made up of eDNA, proteins and exopolysacchrides. Due to their distinct - instrinic, acquired and adaptive - antimicrobial resistance, biofilm formation is one of the m...

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Bibliographic Details
Main Author: Tan, Jun Hou
Other Authors: Michael Givskov
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73866
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Institution: Nanyang Technological University
Language: English