In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm

In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm

With the rapid spread of antimicrobial resistance in Gram-negative pathogens, biofilm-associated infections are increasingly harder to treat and combination therapy with colistin has become one of the most efficient therapeutic strategies. Our study aimed to evaluate the potential for the synergy of...

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Bibliographic Details
Main Authors: Tan, Jun Hou, Vidaillac, Celine, Yam, Joey Kuok Hoong, Chua, Song Lin, Givskov, Michael, Yang, Liang
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2017
Subjects:
LpxC inhibitor
Pseudomonas aeruginosa
Online Access:https://hdl.handle.net/10356/83882
http://hdl.handle.net/10220/42878
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/83882
http://hdl.handle.net/10220/42878

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