Investigating key function-altering mutations in asparaginyl endopeptidase butelase 2

Butelase 2 is a natural protease derived from Clitoria ternatea, the same plant where the fastest known AEP ligase butelase 1 was discovered. The fundamental function of AEP ligases is to macrocyclize cyclotides to achieve ultra-stable forms and new biological functions beneficial to drug discovery...

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Bibliographic Details
Main Author: Ng, Jia Hao
Other Authors: James P. Tam
Format: Final Year Project
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74165
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Institution: Nanyang Technological University
Language: English