Three-dimensional scaffold platform for controlled therapeutic drug and non-viral gene delivery to enhance nerve regeneration and remyelination in spinal cord injuries

• Main Author: Nguyen, Lan Huong
• Other Authors: Chew Sing Yian
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Bioengineering; DRNTU::Science::Medicine::Tissue engineering; DRNTU::Science::Medicine::Biomedical engineering
• Online Access: http://hdl.handle.net/10356/74525
• Institution: Nanyang Technological University

Spinal cord injuries (SCI) are followed by a complex series of events that contribute to the failure of regeneration. To date, there is no repeatable treatment that can restore the injury-induced loss of function. Since damaged spinal axons do not regenerate in their native inhibitory microenvironme...