Three-Dimensional Nanofiber Hybrid Scaffold Directs and Enhances Axonal Regeneration after Spinal Cord Injury

• Main Authors: Milbreta, Ulla, Nguyen, Lan Huong, Diao, Huajia, Lin, Junquan, Wu, Wutian, Sun, Chun-Yang, Wang, Jun, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Neural tissue engineering; Electrospinning; Collagen
• Online Access: https://hdl.handle.net/10356/84116; http://hdl.handle.net/10220/41604
• Institution: Nanyang Technological University

Spinal cord injuries (SCIs) are followed by a complex series of events that contribute to the failure of regeneration. To date, there is no robust treatment that can restore the injury-induced loss of function. Since damaged spinal axons do not spontaneously regenerate in their native inhibitory mic...