Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment

• المؤلفون الرئيسيون: Nguyen, Lan Huong, Gao, Mingyong, Lin, Junquan, Wu, Wutian, Wang, Jun, Chew, Sing Yian
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: RNAi therapy; Protein delivery
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83018; http://hdl.handle.net/10220/42377

Spinal cord injuries (SCI) often lead to persistent neurological dysfunction due to failure in axon regeneration. Unfortunately, currently established treatments, such as direct drug administration, do not effectively treat SCI due to rapid drug clearance from our bodies. Here, we introduce a three-...