Evaluation of an artificial venous valve
Chronic venous insufficiency is a condition whereby the venous valves fail to function properly and result in the backflow of blood. This backflow makes it difficult for blood to return from the lower extremities of a human body back to the heart. There is a need for new prosthetic design to replace...
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Format: | Final Year Project |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | http://hdl.handle.net/10356/75242 |
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Institution: | Nanyang Technological University |
Language: | English |
Summary: | Chronic venous insufficiency is a condition whereby the venous valves fail to function properly and result in the backflow of blood. This backflow makes it difficult for blood to return from the lower extremities of a human body back to the heart. There is a need for new prosthetic design to replace these diseased native venous valves in a human body. In this report, the steps in designing molds for the non-optimized design and optimized design of prosthetic venous valves are presented as well as conduits that are tested for their coadaptation in an in-vitro venous loop setup. Results in this experiment concluded that coadaptation of both designs in the in-vitro venous loop are positive and they can open and close under low pressure and pulsatile frequency. However, the coadaptation of the optimized design is slightly better than the non-optimized design since it can open and close at a lower pump pressure around 60% as compared to the non-optimized design at 65%. |
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