Evaluation of an artificial venous valve

• Main Author: Chua, Yilong
• Other Authors: Munirah Binte Ismail
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/75242
• Institution: Nanyang Technological University

Chronic venous insufficiency is a condition whereby the venous valves fail to function properly and result in the backflow of blood. This backflow makes it difficult for blood to return from the lower extremities of a human body back to the heart. There is a need for new prosthetic design to replace these diseased native venous valves in a human body. In this report, the steps in designing molds for the non-optimized design and optimized design of prosthetic venous valves are presented as well as conduits that are tested for their coadaptation in an in-vitro venous loop setup. Results in this experiment concluded that coadaptation of both designs in the in-vitro venous loop are positive and they can open and close under low pressure and pulsatile frequency. However, the coadaptation of the optimized design is slightly better than the non-optimized design since it can open and close at a lower pump pressure around 60% as compared to the non-optimized design at 65%.