Challenges and solutions in drug-target interaction prediction

• Main Author: Ezzat, Ali
• Other Authors: Kwoh Chee Keong
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Computer science and engineering::Computer applications::Life and medical sciences
• Online Access: http://hdl.handle.net/10356/75771
• Institution: Nanyang Technological University

When a drug is developed, it is designed so that it interacts with a specific target of interest in order to achieve the desired therapeutic effect. However, it is quite common to later find that the developed drug also interacts with multiple other targets that were not intended during its developm...