Discovery of a "first-in-class" plant-derived cystine-stabilized proteasome inhibitor

Cysteine-rich peptides (CRPs) are a group of underexplored compounds between 2 – 8 kDa. Hibiscus sabdariffa was found to be a rich source of CRPs which were named as roseltides. Thus far, eight roseltides rT1 – rT8 have been identified. Roseltide rT1 was previously characterized as a knottin-type hu...

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Bibliographic Details
Main Author: Chan, Leonard Huang Yoon
Other Authors: James P. Tam
Format: Final Year Project
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/76199
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Institution: Nanyang Technological University
Language: English