Discovery of a "first-in-class" plant-derived cystine-stabilized proteasome inhibitor
Cysteine-rich peptides (CRPs) are a group of underexplored compounds between 2 – 8 kDa. Hibiscus sabdariffa was found to be a rich source of CRPs which were named as roseltides. Thus far, eight roseltides rT1 – rT8 have been identified. Roseltide rT1 was previously characterized as a knottin-type hu...
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Format: | Final Year Project |
Language: | English |
Published: |
2018
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Online Access: | http://hdl.handle.net/10356/76199 |
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Institution: | Nanyang Technological University |
Language: | English |