Discovery of inhibitors of deubiquitinase USP21

Ubiquitination plays critical roles in several cellular processes, and are hence potential therapeutic targets against several debilitating human diseases, including cancers. Among various components of the ubiquitin-proteasome system, the deubiquitinases, the enzymes that remove ubiquitin modificat...

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Bibliographic Details
Main Author: Chua, Joanna Hui Xin
Other Authors: Manoj N Krishnan
Format: Final Year Project
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/67176
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Institution: Nanyang Technological University
Language: English