Transdermal liposomes for treatment of atopic dermatitis
Eczema, a skin chronic disorder, is a prevalent inflammatory skin disease. Current treatment methods include the use of systematic immunosuppressant, Cyclosporine and Azathioprine. In recent studies, Methotrexate (MTX) has shown to be a potential treatment of eczema. Indeed, there have been many stu...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2019
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| Online Access: | http://hdl.handle.net/10356/77282 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Eczema, a skin chronic disorder, is a prevalent inflammatory skin disease. Current treatment methods include the use of systematic immunosuppressant, Cyclosporine and Azathioprine. In recent studies, Methotrexate (MTX) has shown to be a potential treatment of eczema. Indeed, there have been many studies done with regards to the encapsulation techniques of various drugs.
This study aims to examine various formulation of liposome and its effect on the release behaviour of the carriers, as well as the skin permeability of the loaded carriers in a porcine model. Drug release profiles were analysed using High Performance Liquid Chromatography (HPLC) and Microplate Reader Analysis. |
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