Transdermal liposomes for treatment of atopic dermatitis
Eczema, a skin chronic disorder, is a prevalent inflammatory skin disease. Current treatment methods include the use of systematic immunosuppressant, Cyclosporine and Azathioprine. In recent studies, Methotrexate (MTX) has shown to be a potential treatment of eczema. Indeed, there have been many stu...
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sg-ntu-dr.10356-772822023-03-04T15:39:05Z Transdermal liposomes for treatment of atopic dermatitis Ong, Amanda Jiamin Subbu S. Venkatraman School of Materials Science and Engineering DRNTU::Engineering::Materials Eczema, a skin chronic disorder, is a prevalent inflammatory skin disease. Current treatment methods include the use of systematic immunosuppressant, Cyclosporine and Azathioprine. In recent studies, Methotrexate (MTX) has shown to be a potential treatment of eczema. Indeed, there have been many studies done with regards to the encapsulation techniques of various drugs. This study aims to examine various formulation of liposome and its effect on the release behaviour of the carriers, as well as the skin permeability of the loaded carriers in a porcine model. Drug release profiles were analysed using High Performance Liquid Chromatography (HPLC) and Microplate Reader Analysis. Bachelor of Engineering (Materials Engineering) 2019-05-23T13:46:52Z 2019-05-23T13:46:52Z 2019 Final Year Project (FYP) http://hdl.handle.net/10356/77282 en Nanyang Technological University 51 p. application/pdf |
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Asia |
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Singapore Singapore |
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English |
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DRNTU::Engineering::Materials |
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DRNTU::Engineering::Materials Ong, Amanda Jiamin Transdermal liposomes for treatment of atopic dermatitis |
| description |
Eczema, a skin chronic disorder, is a prevalent inflammatory skin disease. Current treatment methods include the use of systematic immunosuppressant, Cyclosporine and Azathioprine. In recent studies, Methotrexate (MTX) has shown to be a potential treatment of eczema. Indeed, there have been many studies done with regards to the encapsulation techniques of various drugs.
This study aims to examine various formulation of liposome and its effect on the release behaviour of the carriers, as well as the skin permeability of the loaded carriers in a porcine model. Drug release profiles were analysed using High Performance Liquid Chromatography (HPLC) and Microplate Reader Analysis. |
| author2 |
Subbu S. Venkatraman |
| author_facet |
Subbu S. Venkatraman Ong, Amanda Jiamin |
| format |
Final Year Project |
| author |
Ong, Amanda Jiamin |
| author_sort |
Ong, Amanda Jiamin |
| title |
Transdermal liposomes for treatment of atopic dermatitis |
| title_short |
Transdermal liposomes for treatment of atopic dermatitis |
| title_full |
Transdermal liposomes for treatment of atopic dermatitis |
| title_fullStr |
Transdermal liposomes for treatment of atopic dermatitis |
| title_full_unstemmed |
Transdermal liposomes for treatment of atopic dermatitis |
| title_sort |
transdermal liposomes for treatment of atopic dermatitis |
| publishDate |
2019 |
| url |
http://hdl.handle.net/10356/77282 |
| _version_ |
1759856907689918464 |