CRISPR-based epigenome editing for targeted gene regulation
The discovery of CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technology has increased the repertoire of methods to target and test specific gene functions. CRISPR-Cas system has been modified by fusing epigenetic modifiers to a “dead” Cas9 endonuclease (dCas9) to...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2019
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| Online Access: | http://hdl.handle.net/10356/79000 |
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| Institution: | Nanyang Technological University |
| Language: | English |