Improving acetate tolerance of Escherichia coli by rewiring Its global regulator cAMP receptor protein (CRP)
The presence of acetate exceeding 5 g/L is a major concern during E. coli fermentation due to its inhibitory effect on cell growth, thereby limiting high-density cell culture and recombinant protein production. Hence, engineered E. coli strains with enhanced acetate tolerance would be valuable for t...
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| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/79959 http://hdl.handle.net/10220/18294 |
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| Institution: | Nanyang Technological University |
| Language: | English |