Type I IFN signaling in CD8– DCs impairs Th1-dependent malaria immunity
Many pathogens, including viruses, bacteria, and protozoan parasites, suppress cellular immune responses through activation of type I IFN signaling. Recent evidence suggests that immune suppression and susceptibility to the malaria parasite, Plasmodium, is mediated by type I IFN; however, it is uncl...
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Main Authors: | Varelias, Antiopi, Hertzog, Paul J., Kalinke, Ulrich, Montes de Oca, Marcela, James, Kylie R., Ammerdorffer, Anne, Edwards, Chelsea L., de Labastida Rivera, Fabian, Amante, Fiona H., Bunn, Patrick T., Sheel, Meru, Sebina, Ismail, Koyama, Motoko, Haque, Ashraful, Best, Shannon E., Gun, Sin Yee, Rénia, Laurent, Ruedl, Christiane, MacDonald, Kelli P.A., Hill, Geoffrey R., Engwerda, Christian R. |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/80006 http://hdl.handle.net/10220/20014 |
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Institution: | Nanyang Technological University |
Language: | English |
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