Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo
In this study, we applied structure-based virtual screening techniques to identify natural product or natural product-like inhibitors of iNOS. The iNOS inhibitory activity of the hit compounds was characterized using cellular assays and an in vivo zebrafish larvae model. The natural product-like com...
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Main Authors: | Zhong, Hai-Jing, Liu, Li-Juan, Chong, Cheong-Meng, Lu, Lihua, Wang, Modi, Chan, Daniel Shiu-Hin, Chan, Philip Wai Hong, Lee, Simon Ming-Yuen, Ma, Dik-Lung, Leung, Chung-Hang |
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Other Authors: | Verma, Chandra |
Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/80047 http://hdl.handle.net/10220/19501 |
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Institution: | Nanyang Technological University |
Language: | English |
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