Micro-optical coherence tomography tracking of magnetic gene transfection via Au–Fe3O4 dumbbell nanoparticles

• Main Authors: Shi, Wei, Liu, Xinyu, Wei, Chao, Xu, Zhichuan J., Sim, Stanley Siong Wei, Liu, Linbo, Xu, Chenjie
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2016
• Subjects: Heterogeneous nanoparticles; Magnetofection; Gene delivery; Dumbbell nanoparticles; Micro-optical coherence tomography
• Online Access: https://hdl.handle.net/10356/80244; http://hdl.handle.net/10220/40456
• Institution: Nanyang Technological University

Heterogeneous Au-Fe3O4 dumbbell nanoparticles (NPs) are composed of Au NPs and Fe3O4 NPs that bring in optical and magnetic properties respectively. This article reports the engineering of Au-Fe3O4 NPs as gene carriers for magnetic gene transfection as well as contrast agents for micro-optical coher...