Lipodisks integrated with weak affinity chromatography enable fragment screening of integral membrane proteins

Membrane proteins constitute the largest class of drug targets but they present many challenges in drug discovery. Importantly, the discovery of potential drug candidates is hampered by the limited availability of efficient methods for screening drug-protein interactions. In this work we present a n...

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Bibliographic Details
Main Authors: Duong-Thi, Minh-Dao, Bergström, Maria, Edwards, Katarina, Eriksson, Jonny, Ohlson, Sten, To Yiu Ying, Janet, Torres, Jaume, Agmo Hernández, Víctor
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/80267
http://hdl.handle.net/10220/40453
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Institution: Nanyang Technological University
Language: English