Fragment Screening of Human Aquaporin 1

Fragment Screening of Human Aquaporin 1

Aquaporins (AQPs) are membrane proteins that enable water transport across cellular plasma membranes in response to osmotic gradients. Phenotypic analyses have revealed important physiological roles for AQPs, and the potential for AQP water channel modulators in various disease states has been propo...

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Bibliographic Details
Main Authors: To, Janet, Torres, Jaume
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Human aquaporin 1
Fragment based drug discovery
Surface plasmon resonance
Thermal shift
Membrane protein
Online Access:https://hdl.handle.net/10356/80531
http://hdl.handle.net/10220/40530
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/80531
http://hdl.handle.net/10220/40530

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