Artemisinin resistance in Plasmodium falciparum
Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibi...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/80268 http://hdl.handle.net/10220/40410 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibility is maintained in mature stages. However, the clinical relevance of this finding to treatment failure is unclear since these infections could still be successfully treated with artemisinin combination therapies. |
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