Artemisinin resistance in Plasmodium falciparum

Artemisinin resistance in Plasmodium falciparum

Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibi...

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Main Authors: Lun, Zhao-Rong, Ferreira, Pedro E, Fu, Lin-Chun
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
antimalarial agent
Falciparum
Online Access:https://hdl.handle.net/10356/80268
http://hdl.handle.net/10220/40410
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Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-80268
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spelling sg-ntu-dr.10356-802682023-02-28T16:56:29Z Artemisinin resistance in Plasmodium falciparum Lun, Zhao-Rong Ferreira, Pedro E Fu, Lin-Chun School of Biological Sciences antimalarial agent Falciparum Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibility is maintained in mature stages. However, the clinical relevance of this finding to treatment failure is unclear since these infections could still be successfully treated with artemisinin combination therapies. Accepted version 2016-04-14T07:09:05Z 2019-12-06T13:46:13Z 2016-04-14T07:09:05Z 2019-12-06T13:46:13Z 2014 2014 Journal Article Lun, Z.-R., Ferreira, P. E. & Fu, L.-C. (2014). Artemisinin resistance in Plasmodium falciparum. The Lancet Infectious Diseases, 14(6), 450-451. 1473-3099 https://hdl.handle.net/10356/80268 http://hdl.handle.net/10220/40410 10.1016/S1473-3099(14)70706-6 178970 en The Lancet Infectious Diseases © 2014 Elsevier. This is the author created version of a work that has been peer reviewed and accepted for publication by Lancet Infectious Diseases, Elsevier. It incorporates referee’s comments but changes resulting from the publishing process, such as copyediting, structural formatting, may not be reflected in this document. The published version is available at: [http://dx.doi.org/10.1016/S1473-3099(14)70706-6]. 2 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic antimalarial agent
Falciparum
spellingShingle antimalarial agent
Falciparum
Lun, Zhao-Rong
Ferreira, Pedro E
Fu, Lin-Chun
Artemisinin resistance in Plasmodium falciparum
description Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibility is maintained in mature stages. However, the clinical relevance of this finding to treatment failure is unclear since these infections could still be successfully treated with artemisinin combination therapies.
author2 School of Biological Sciences
author_facet School of Biological Sciences
Lun, Zhao-Rong
Ferreira, Pedro E
Fu, Lin-Chun
format Article
author Lun, Zhao-Rong
Ferreira, Pedro E
Fu, Lin-Chun
author_sort Lun, Zhao-Rong
title Artemisinin resistance in Plasmodium falciparum
title_short Artemisinin resistance in Plasmodium falciparum
title_full Artemisinin resistance in Plasmodium falciparum
title_fullStr Artemisinin resistance in Plasmodium falciparum
title_full_unstemmed Artemisinin resistance in Plasmodium falciparum
title_sort artemisinin resistance in plasmodium falciparum
publishDate 2016
url https://hdl.handle.net/10356/80268
http://hdl.handle.net/10220/40410
_version_ 1759856450092400640

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